DAEDALUS
ADvAnced 4D biomAteriaLs for mucosa and sub-mUcosa treatment in patients affected by intestinal diSeases
DAEDALUS is a Horizon Europe-funded research project aiming to transform the treatment of colorectal diseases (CRDs) through a new generation of minimally invasive, regenerative solutions. These diseases, such as ulcerative colitis and familial adenomatous polyposis, currently require invasive surgery with serious long-term consequences.
DAEDALUS proposes an alternative: the replacement of damaged tissues using injectable 4D biomaterials, enriched with therapeutic molecules and patient-derived cells. The goal is to restore tissue function while reducing complications and improving quality of life.
What makes DAEDALUS unique?
- 4D biomaterials that adapt their shape after injection to match tissue architecture
- Controlled drug delivery: biomolecules are released over time to support healing
- Smart nanoparticles and engineered grids to guide cell growth and structure
- Endoscopic toolhead for in situ application with existing clinical devices
This combination enables targeted, patient-specific therapies with reduced surgical burden.
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