OUR TEAM
Staff Members
Peter Dubruel, Prof.
Professor and Group leader
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Sandra Van Vlierberghe, Prof.
Professor and Group leader
Prof. Dr. Sandra Van Vlierberghe holds a guest professorship at Vrije Universiteit Brussel (Brussels Photonics, VUB, Belgium) and a 100% professorship (BOF-ZAP) at Ghent University (Polymer Chemistry & Biomaterials Group, Belgium). She has acquired expertise related to the synthesis, the modification and the processing of photo-responsive and/or photo-crosslinkable (bio)polymers including thermoplasts (e.g. polyesters) and hydrogels (e.g. proteins and polysaccharides) for a variety of biomedical applications (e.g. tissue engineering, drug delivery, sensors, photonics, etc.). She is experienced in the field of polymer processing using 3D printing (laser- versus extrusion-based additive manufacturing), electrospinning and two-photon polymerization (2PP). She received her PhD in Sciences in 2008 at Ghent University. She authored >165 Web of Science Core Collection cited papers, she has a h-index of 32 (WoS), is promoter of 17 PhD’s and she edited three books, authored 7 chapters in books of which 5 invited. She is treasurer of the Belgian Polymer Group (BPG), former spokesperson of the ‘Young Scientist Forum (YSF)’, TERMIS-EU council member and member of the independent ESB Awards Committee. She serves on the editorial board of several journals focussing on tissue engineering. In 2017, she received the Jean Leray award from the European Society for Biomaterials. She is (co-)inventor of numerous patents and patent applications, is co-founder of the spin-off ‘XpectINX’ focussing on bioinks for biofabrication purposes and is involved in the spin-off project Gelgraft Medical.
Lab Coordinator
Veerle graduated as ‘industrieel ingenieur chemie – algemene chemie’ in 1994 at KIHO (Ghent, Belgium). As Erasmus student she worked during her thesis on chemical recycling of PET to polyol at the Fachhochschule Aalen (Germany). After her thesis she stayed another 3 years in Germany to work for a PUR company where she got the chance to scale up the chemical recycling of PET to polyol and to use the recyclate in their PUR production. As at that time a Belgium diploma was not accepted/recognized in Germany, she combined work and study in order to obtain a German work permit. In 1996 she graduated as ‘Diplom Ingenieur Polymerchemie’ at the FH Aalen (Germany)
In 1997 she moved back to Belgium to work as chemical engineer in the International Development Centre of Recticel. After half a year she got an offer from the Gates Europe Company and started working there as Material Development Engineer. In 2000 Veerle decided to work as chemical engineer for the Philips company and stayed there until September 2007. Since then she has been working as lab manager for the UGent PBM group. Inspired by the PhD students she is besides being a lab manager also involved in scientific work and is currently working on nitric oxide releasing polymers as therapeutic delivery of exogenous NO.
Postdoctoral Researchers
Dr. Aysu Arslan
Biography: Aysu obtained her bachelor and master degrees in Department of Chemical Engineering, Hacettepe University (Turkey). In her master thesis, she focused on the fabrication of boron-doped polyester/hydroxyapatite composite electrospun scaffolds for bone tissue engineering applications under the supervision of Prof. Menemse Gumusderelioglu. After obtaining her master degree in 2015, she started her research activities in PBM Group working on an IOF project as scientific co-worker in close collaboration with Allnex coating resins company. In 2017, she started her PhD studies working on FWO project in Department of Organic and Macromolecular Chemistry (UGent) as part of PBM Group. During her projects and PhD research, she focused on the design and development of biocompatible urethane-based photo-crosslinkable polymer precursors and their applications in various additive manufacturing techniques, in particular deposition-based 3D printing and multiphoton lithography. During her master and PhD studies, she co-authored 7 peer-reviewed papers, 1 patent and participated in multiple international conferences. After obtaining her PhD in 2020, she started to work as a postdoctoral researcher on IOF Stepstone project Xpect-INX, which is a spin-off project of Ghent University for the commercial translation of specialized (bio)inks for 3D (bio)printing.
Current project: XPECT-INX®
Dr. Ágnes Dobos
Biography: Ágnes earned her BSc in Biochemical Engineering at the Technical University of Budapest in 2014. She continued her studies in Sweden and Austria and received MSc double degree in Tissue Engineering and Medical Biosciences at FH Wien and the University of Linköping in 2016. She joined Vienna University of Technology (TU Wien) in 2016 where she obtained her PhD in Technical Chemistry. She joined the IOF Stepstone Project XPECT-INX, a spin-off project for the commercialization of bioinks for 3D (bio)printing in 2019 at Ghent University. Her research interests lie in the area of high resolution laser based additive manufacturing technologies, biofabrication, biomimetic in vitro 3D cellular models and organ-on-chip devices.
Current project: XPECT-INX®
Dr. Tom Gheysens
Biography: Tom obtained his MSc in Biology at Ghent University in Belgium. In the following two years he was involved in a project exploring the use of silk and spider silk in biomedical applications, with a focus on soft tissue engineering (cartilage). Afterwards he obtained his DPhil at Oxford University (UK) with his thesis focusing at “small molecules in silk”, looking at how small molecules influence the folding of proteins with implications for protein-based biomaterials and certain diseases. At his 2 year fellowship at ESA he was involved in projects like : a biosensor from structural proteins by coupling light into structural proteins which proves to be an extremely sensitive biosensor, the development of new radiation protection suits for human long term space duration travel to mars and human hibernation.
In 2013, he obtained a MarieCurie fellowship with title “Natural functional plasticizers for controlled protein folding and extrusion into biomaterials” focused on de development of a natural extrusion set-up for proteins.
Currently he is working on the DERMA project for making diagnostic, odor absorbing and antibacterial dressings for wounds.
Current project: DERMA
Dr. Jasper Van Hoorick
Biography: Jasper received an Agoria award for his chemical master thesis on tissue engineering applications in 2014. In 2015 he obtained an FWO (Research Foundation Flanders) grant for a PhD project at Ghent University and Vrije Universiteit Brussel. He focussed on the development of biodegradable polymer materials for ocular tissue regeneration. A large part of this research focussed on the development and processing of materials using multiphoton lithography leading to 20 Web of Science Core Collection papers, 1 book chapter, and 2 patents. In 2018 he aided in consolidating FWO funding to develop the corneal membranes towards (pre)clinical applications. In 2019 he graduated summa cum laude with felicitations of the jury as PhD at Ghent University and Vrije Universiteit Brussel. This achievement was also crowned with a SOLVAY award in 2020. Currently, he is leading the spin-off project “XPECT-INX” which focusses on the commercialisation of innovative materials and bioinks for 3D bioprinting or biofabrication.
Current project: XPECT-INX®
PhD Students
Özge Begüm Akalin
Biography: Begüm obtained her bachelor degree in Department of Chemical Engineering, Middle East Technical University (Turkey) and her master degree in Department of Biomedical Science and Engineering, Koc University (Turkey). In her master thesis, she studied the dynamics of single-cell motility on fibrous collagen containing semi-synthetic polyethylene glycol hydrogels. After obtaining her master degree, she started her research activities in PBM Group in 2016. During her PhD research, she focused on the application of photopolymerized acrylate-terminated urethane-based polyethylene oxide (PEO) hydrogel precursors (AUP) as porous scaffolds for meniscal tissue engineering while using deposition-based 3D printing. This approach enables to create a tissue engineered, patient specific 3D-printed meniscus with tunable physical properties not only via altering the design but also via altering the backbone molecular weight of the AUPs.
Current project: Acrylate-Terminated Urethane-Based Hydrogel Precursors for Meniscus Tissue Engineering
Nathan Carpentier
Biography: Nathan graduated as Master of Science at the University of Antwerp in 2017. During the final year of his Masters degree, he performed his Master thesis at Janssen Pharmaceutica on the synthesis of small molecules in order to develop a drug to cure a certain viral disease. During his thesis Nathan really got interested in the process of drug development.
After his graduation, Nathan decided to start a PhD within the PBM research group. With his PhD he could combine his both interests in drug development and polymer chemistry.
His topic deals with the development of an in vitro model of the liver to detect the hepatotoxicity of drug compounds during the preclinical phase.
To obtain this goal he modifies polysaccharides and proteins towards crosslinkable hydrogel building blocks. These hydrogels are printed using different 3D-printing techniques to obtain scaffolds for hepatocyte seeding.
Current project: Acrylate-Terminated Urethane-Based Hydrogel Precursors for Meniscus Tissue Engineering
Lauren De Grave
Biography: In 2013, Lauren started her Bachelor’s in Chemistry at Hasselt University, after which she continued to a Master’s in Chemistry at KU Leuven. In 2018, she obtained her Master’s degree in Chemistry with specialization in organic synthesis after completing a Master’s thesis in the laboratory of Prof. Wim Dehaen. This research focused on the synthesis, functionalization and optimization of new thiacyclophane structures with the possibility to trap metal ions in its cavity and with a potential application in kidney dialysis. After graduating, she started working on a PhD project in polymer chemistry at KU Leuven in the research group of Prof. Mario Smet. This doctoral research focused on the development and optimization of several organic compounds (monomers, polymers, dispersants and additives) as organic matrix for the preparation of ceramic slurries with beneficial properties for 3D printing of dental prostheses. Currently, she's working on the project GREENER, which focuses on the development of a biobased and biodegradable alternative for the water-soluble and wide-spread polyacrylic acid.
Current project: GREENER
Lobke De Vos
Biography: Lobke started her Bachelor of science in Chemistry at the University of Ghent in 2015 after which she continued with a Master’s in chemistry focussed on materials chemistry. Despite the major of her Master’s, she caught an interest in polymers for biomedical applications and by consequence performed her Master’s thesis within the PBM group. The research involved the synthesis, characterisation and processing of poly(alkylene terephthalates) to be used as cardiovascular bypass graft. After her graduation in June 2020, she stayed in the PBM research group and started working as a PhD researcher on an FWO project which includes the development and characterisation of shape-memory polymers and gelatine derivatives for corneal tissue engineering.
Current project: Introducing smart polymers in the field of corneal endothelial tissue engineering: solving a blinding disease
Jasper Delaey
Biography: Jasper Delaey received his MSc. degree in chemistry from Ghent University in 2018. His research focusses on the application of biodegradable, shape-memory materials in corneal tissue engineering. He completed his thesis in and is currently pursuing his PhD in this topic. In 2019 he was award for the best master thesis by the Belgian Polymer Group (BPG) and the Royal Flemish Chemical Society (KVCV).
Current project: Smart polymers to tackle a blinding disease: Corneal endothelial tissue engineering
Chloë Geeroms
Biography: Chloë is a joint-PhD candidate in Biomedical Sciences and Natural Sciences at KU Leuven and UGent, respectively. Her research project focusses on Novel Polymer Materials and 3D Scaffolds for Skeletal Muscle Tissue Engineering. Prior to this project, she conducted research at UGent for two years and she co-authored one publication resulting from her master thesis project at KU Leuven KULAK. In 2016, Chloë earned a Master’s degree in Biochemistry and Biotechnology from KU Leuven.
Current project: 3D4MED
Coralie Greant
Biography: Coralie Gréant graduated as a Biomedical Engineer in 2016 in a joint program of Vrije Universiteit Brussel and Ghent University. She spent the first year of her career in a start-up company focusing on 3D-printing, where she cooperated with orthopedic surgeons in the context of bone tumor resections and reconstructions. Subsequently, she worked as an account manager in the Benelux, gaining sales experience in the Biotech and Biomedical industry. Coralie is currently performing a PhD at Ghent University in the group of polymer chemistry and biomaterials, in which she is focusing on 3D-printing of smart biomaterials towards minimally invasive breast reconstruction. She combines this with the coordination of the Interreg project MATMED, for which her main focus is to support SMEs in bringing their innovation to the market.
Current projects:
Smart biomaterials towards minimally invasive breast reconstruction
Shraavya Shastry Kallaje
Biography: Shraavya obtained her Bachelors in Biomedical Engineering in 2016 from Visvesvaraya Technological University, Karnataka, India. She moved to Ghent, Belgium in 2017 to pursue MSc. In Biomedical Engineering at Ghent University, with a thesis focused on peripheral nerve regeneration using plasma treated polymeric conduits in the research group of Prof. Dr. Ir. Nathalie De Geyter (PLASMATS, Ghent University, Belgium). In 2019, Shraavya started as a research intern with Prof. Dr. Peter Dubruel, working on the project DERMA with Dr. Tom Gheysens and continuing further on her interest in biomaterials, she started a PhD with the group in 2020.
Current project: to be announced
Martina Meazzo
Biography: Martina graduated in 2017 in Biomedical Engineering at Genoa University (Italy) with a score of 103/110. After that, she continued to a Master’s in Biomaterials and Rehabilitation Engineering still at Genoa University and graduated in 2019 with a score of 110/110 cum laude. She performed her Master thesis traineeship in PBM and after that experience, she was given the opportunity to start a joint PhD between Gent University and Genoa University.
She's working the project BioMeniscus which aims the development of an artificial meniscus implant through 3D printing based on an innovative polymer with unique properties.
Current project: BioMeniscus - Development of an artificial meniscus through 3D polymer printing
Manon Minsart
Biography: Manon graduated as a Master of Chemistry in July 2018. During her master thesis at the PBM group, she gained a strong interest for polymers and their plethora of biomedical applications, which have contributed immensely to improve human health. After her graduation, Manon was given the opportunity to stay and start a PhD in the PBM group. In December 2018, she obtained a FWO-SB fellowship titled ‘Development of a smart diagnostic antimicrobial hydrogel-based wound dressing’. Her project focuses on the development of a ‘smart’ burn wound dressing using patented PEG-based acrylate-endcapped urethane-based hydrogel precursors (AUPs), which are mainly processed through (co-axial) electrospinning.
Current project: Development of a smart diagnostic antimicrobial hydrogel-based wound dressing
Georgios Misiakos
Biography: George received his bachelor’s degree in Chemistry from the University of Athens and his master’s degree in Chemistry from the University of Groningen where he followed the track of Catalysis and Green chemistry. His thesis was a total synthesis project in the group of prof. dr. ir. A.J. (Adriaan J) Minnaard where he synthesized two mycobacterial glycolipids, DAT1a and DAT3, which are investigated for their immunological properties in the research for new treatments against tuberculosis. His internship was performed during a 6-month period in the company INNOSYN B.V where he worked on optimizing the synthesis of an anti-epileptic drug. Since April 2020 he joined the group of prof. Sandra Van Vlierberghe to contribute with his organic chemistry background to the fascinating polymer chemistry performed in the group.
Current project: Acrylate-endcapped urethane-based polymers for the development of iodine-based antibacterial wound dressings
Laurens Parmentier
Biography: Laurens combines his material knowledge from his BSc in chemical engineering and materials science at Ghent University (2017) with the know-how obtained knowledge from his international MSc in biomedical engineering which was followed at Ghent University, Vrije Universiteit Brussel and Trinity College Dublin (2019). His second year at Trinity College Dublin was orientated towards acquiring research experience within bone tissue engineering. Currently, he is working at the Polymer Chemistry & Biomaterials Group on an FWO-funded project: Capturing the biophysical cues of bone to stimulate regeneration in critical-sized defects, where (bio)polymer synthesis and characterisation is combined with processing towards dual core-shell 3D-bioprinted patient-specific implants.
Current project: Capturing the biophysical cues of bone to stimulate regeneration in critical bone defects
Nele Pien
Biography: Nele graduated in a Master of Science in Biomedical Engineering in a joint Master program of Ghent University and Vrije Universiteit Brussel. In her master thesis, in the Polymer Chemistry and Biomaterials (PBM) group (Ghent University), she focused on the development of patient-specific 3D-printed scaffolds for meniscus tissue engineering (TE). Nele is currently a joint-PhD student in the PBM group (Prof. P. Dubruel and Prof. S. Van Vlierberghe) and in the Laboratory for Biomaterials and Bioengineering (LBB) (Prof. D. Mantovani) at the Laval University (Quebec, Canada). In 2019, she was granted a Vanier Canada Graduate Scholarship. Her PhD research focuses on the development of tubular scaffolds for TE and regenerative medicine (TERM) applications including (1) the development of a physiologically-relevant model of the vascular wall and (2) the development of tubular scaffolds for deep flexor tendon repair.
Current project: Design, development and validation of a physiologically-relevant model of the vascular wall
Inez Roegiers
Biography: Inez graduated as a Master of Biomedical Sciences (specialization: Environmental Health Sciences) in July of 2019 at Hasselt University. She did her master thesis on the application of electroactive bacteria for wastewater purification at the X-lab (Hasselt university) and the Center for Microbial Ecology and Technology (CMET, Ghent University). After this, her interest in the diverse application potential of microbial communities was spiked but she wanted to go back to her biomedical roots by applying to a project that had it all: the 3D intestine FWO project. This project aims to develop an in vitro model for the small intestinal ecosystem by combining a microbial community, human cell lines, hydrogels and 3D printing. She officially started as a PhD student on the 3D intestine project in May of 2019.
Current project: 3D Biomimetic model of the host-microbiome small intestinal
ecosystem
Anna Szabó
Biography: Anna has obtained a BSc and MSc degree in chemical engineering majoring in material science at the Budapest University of Technology and Economics in 2019. She was awarded with a second place for her master thesis “Immobilization and bioimprinting of lipases in polyaspartamide nanofibers” on the Hungarian Junior Science Conference, in 2019. The same year she earned an Erasmus+ scholarship in the PBM group. In that period, her research focussed on the development of biocompatible urethane-based photo-crosslinkable polymer materials towards additive manufacturing applications. In her PhD, she’s involved with Fish-AI project under the egis of Horizon2020 FET-OPEN, which aims to develop an artificial in vitro fish intestine model towards sustainable fish farming.
Current project: FISH-AI
Quinten Thijssen
Biography: Quinten obtained his bachelor’s degree in chemistry in 2017 after which he started his master’s with as major ‘Molecular and macromolecular design’ and minor ‘Research and development’ at the University of Ghent (Belgium). During his master’s, he performed a joint master thesis in the research groups of Prof. Filip Du Prez (PCR group, UGent, Belgium) and Prof. Haritz Sardon (Innovative polymers group, POLYMAT, Spain) working on the combination of photochemistry and vitrimers. More specifically, the goal of his master thesis was to employ photoacid and photobase generators in order to control the kinetics of the transamination reaction in vinylogous urethane vitrimers. In 2019, Quinten graduated as master in chemistry (magna cum laude). After which, as a result of his interest in polymers for biomedical applications, he started his PhD under supervision of Prof. Sandra Van Vlierberghe in the PBM group (UGent, Belgium). Since 2020, Quinten is working as an FWO-SB fellow on the development of a biodegradable implant for maxillofacial reconstruction (promotor: Sandra Van Vlierberghe, co-promotor: maxillofacial surgeon Robin Willaert).
Current project: Development of a biodegradable bone graft for maxillofacial reconstruction
Lenny Van Daele
Biography: Lenny Van Daele is a polymer chemist with a distinct interest in polymers for biomedical applications. He obtained both his Bachelor’s and Master’s Degree at Ghent University, where he is currently working as a PhD candidate. During his master thesis, he worked on the development of a wound dressing for the treatment of chronic wounds. His PhD project is funded by the Research Foundation in Flanders (FWO) and focusses on the development of new polymers for cardiovascular applications, as well as surface modifications and processing using 3D-printing technology.
Current project: Shape memory polymers based on poly(alkylene terephthalate)s for an improved cardiovascular stent
Lana Van Damme
Biography: Lana Van Damme, MD received her medical degree from the University of Ghent in 2018, where she will start her residency in the Department of Plastic and Reconstructive Surgery in 2022. In 2018, she obtained an FWO-SB mandate for an interdisciplinary PhD project between the faculty of Sciences of Ghent University in the Polymer Chemistry & Biomaterials Research group (PBM) and the Department of Plastic and Reconstructive Surgery. Her PhD focusses on the development of 3D printed core/shell hydrogels towards patient-specific breast reconstruction.
Current project: Development of 3D printed core/shell hydrogels towards patient specific breast reconstruction
Babs Van De Voorde
Biography: Babs graduated as a Master of Chemistry in 2017 at the University of Ghent, with organic and polymer chemistry as main topics. She did her master thesis in the research group of Prof. Du Prez (PCR, UGent) and was involved with the successful search of greener synthesis routes towards sustainable urazoles and their applications in polymer chemistry (dendrimers and hyperbranched polymers). In 2018, Babs became a PhD student in the research group of Prof. Van Vlierberghe (PBM, UGent) in the newly funded SBO project RELFICOM, running in the NANOFORCE program of SIM flanders. In collaboration with various Belgian universities and companies, she represents the chemical part in the project. Her part aims the development of more reliable composite structures with enhanced properties, starting from recycled PET and recycled carbon fibers. Therefore, various processing techniques are used, including extrusion, compression molding, fused deposition modelling and electrospinning.
Current project: RELFICOM – Reliability of fibre-reinforced composites: materials design and variability
Evelien Vermoesen
Biography: Evelien graduated in 2018 as master of science in chemistry at Ghent University. She did her thesis research in PBM group investigating slow release antibacterial wound dressings for burn wound applications. During the thesis she got the opportunity for a Baekeland doctorate application handling the development of a slow release biodegradable coating for organic fertilizers. For this project, she will work in collaboration with the ISOFYS research group and the fertilizer comapany Fertikal n.v..
Current project: Baekeland VLAIO project
Jan-Philip Zegwaart
Biography: Jan-Philip obtained his MSc Biomedical Engineering at Twente University (NL) in 2013, with a thesis on “Modification of gold manoparticles with PEG and fluorophore labelled antibodies” (Nanobiophysics department). Later in 2013 Jan-Philip moved to Belgium. In 2015 he obtained a BA in Philosophy (KU Leuven) with a provocative thesis on human enhancement. After that, he became a researcher and lecturer at Artesis Plantijn Hogeschool (Antwerp).
In 2017, Jan-Philip started his doctoral studies at Ghent University (Polymer Chemistry and Biomaterials Group). His doctoral research concerns the development of a post-surgical wound care solution for chronic rhinosinusitis. In this project, Jan-Philip has been developing acrylate-endcapped urethane-based polymer (AUP) resins that can be used in stereolithographic (SLA) 3D-printing applications. This research is done in close collaboration with the Ghent University hospital (Department of Head and Skin and the Department of Otorhinolaryngology) and the Advanced Manufacturing Lab (Manufacturing Processes and Systems department, KU Leuven).
Current project: Acrylate-endcapped urethane-based polyethylene glycol polymers for post-surgical chronic rhinosinusitis treatment
Other
Erik Devroe
Technician in XPECT-INX
Biography: Erik studied biotechnology at the Howest in Bruges specializing in pharmaceutical and biological sciences. Because of his strong interest in organic chemistry he helped with the development of antimitotic peloruside-analogues for cancer treatment at UGhent department for organic and macromolecular chemistry for his bachelor’s thesis. Later he returned to UGhent as lab technician for the upcoming spinoff Xpect-InX. His focus being the development of DLP bioink resins, synthesis of novel photoinitiators and improvement of polymer syntheses.
Current project: XPECT-INX®
Thesis Students
Karen De Man
Supervisor: Coralie Gréant
Pieter De Ridder
Supervisor: Coralie Gréant
Valérie Stragier
Supervisor: Coralie Gréant
Silke Maes
Supervisor: Coralie Gréant
Elisa Ghesquiere
Supervisor: Coralie Gréant
Bo Van Durme
Supervisor: Coralie Gréant
Marie Maertens
Supervisor: Nathan Carpentier
Gizem Cantörü
Supervisor: Nathan Carpentier
Kim Cornelis
Supervisor: Quinten Thijssen
Astrid Quaak
Supervisor: Quinten Thijssen
Milan Debie
Supervisor: Tom Gheysens
Laura Verhasselt
Supervisor: Tom Gheysens
Inneke De Mesmaeker
Supervisor: Manon Minsart
Nicolas Deroose
Supervisor: Manon Minsart
Sophie D'Haese
Supervisor: Laurens Parmentier
Oriana Nobus
Supervisor: Laurens Parmentier
Elise Demuynck
Supervisor: Anna Szabó
Lise Vermeir
Supervisor: Anna Szabó
Robin Colenbier
Supervisor: Babs Van de Voorde
Sven Vereecken
Laura Meyers
Supervisor: Lana Van Damme
Robrecht Lippens
Supervisor: Chloë Geeroms
Laura Govaert
Supervisor: Lenny Van Daele
Kim Vanbeversluys
Supervisor: Inez Roegiers